FBXW8 antibody

Catalog Number:

31961

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5T3J3
NCBI Gene ID: NP_699179

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Synthetic peptide of human FBXW8

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

References:

appl_detail:

IHC dilution:1:50-1:300

Datasheet PDF