CHRND antibody

Catalog Number:

31951

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BW62
NCBI Gene ID: NP_000742

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Synthetic peptide of human CHRND

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

IHC dilution:1:25-1:50

Datasheet PDF