Exendin 4 antibody

Catalog Number:

31945

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6DN90
NCBI Protein#: AAB22006

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Synthetic peptide of Heloderma suspectum Exendin 4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

ELISA

Background:

Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.

References:

appl_detail:

Datasheet PDF