1-832-868-1888
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Catalog Number: |
31928 |
| other_names: | DPH4; JJJ3; ZCSL3 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q14526 |
Form of Antibody: |
pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human DNAJC24 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
|
Applications: |
IHC |
Background: |
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). |
References: |
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appl_detail: |
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