SPACA1 antibody

Catalog Number:

31896

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q7L513
NCBI Protein#: BC029488

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human SPACA1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

References:

appl_detail:

WB dilution:1:1000-1:5000

Datasheet PDF