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MED17 Polyclonal Antibody

Catalog Number:

31626
other_names: MED17; CRSP6; CRSP77; DRIP80; TRAP80; SRB4; mediator complex subunit 17

Amount:

100μg
calculated_mw: 80kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NVC6
NCBI Gene ID:9440

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human MED17 (NP_004259.3).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

References:

appl_detail:

WB 1:500 - 1:2000

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