MS4A2 Polyclonal Antibody

Catalog Number:

31594

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q01362
NCBI Gene ID:2206

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human MS4A2 (NP_000130.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF