RNF34 Polyclonal Antibody

Catalog Number:

31584

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q969K3
NCBI Gene ID:80196

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human RNF34 (NP_079402.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF