SHOX2 Polyclonal Antibody

Catalog Number:

31502

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O60902
NCBI Gene ID:6474

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SHOX2 (NP_003021.3).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF