VNN2 Polyclonal Antibody

Catalog Number:

31458

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95498
NCBI Gene ID:8875

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human VNN2 (NP_004656.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF