1-832-868-1888
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Catalog Number: |
31350 |
| other_names: | ANKS1B; AIDA; AIDA-1; ANKS2; EB-1; EB1; cajalin-2; ankyrin repeat and sterile alpha motif domain containing 1B |
Amount: |
100μg |
| calculated_mw: | 80kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q7Z6G8 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human ANKS1B (NP_858056.2). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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