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Catalog Number: |
31330 |
| other_names: | FBXW11; BTRC2; BTRCP2; FBW1B; FBXW1B; Fbw11; Hos; F-box/WD repeat-containing protein 11 |
Amount: |
100μg |
| calculated_mw: | 62kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q9UKB1 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human FBXW11 (NP_387448.2). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF |
Background: |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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