ACR Antibody

Catalog Number:

31300

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P10323
Gene ID:49

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 407-421 amino acids of human acrosin

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ACR protein.

Applications:

ELISA WB

Background:

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

References:

appl_detail:

Predicted MW: 46kd
ELISA: 1:1000-1:2000
Western blotting: 1:200-1:1000

Datasheet PDF