PAK1 Antibody

Catalog Number:

31287

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13153
Gene ID:5058

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 225-238 amino acids of Human p21 protein (Cdc42/Rac)-activated kinase

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PAK1 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Predicted MW: 61kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF