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SPAG4 Antibody

Catalog Number:

31271
other_names: Sperm associated antigen 4, SUN4, CT127

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NPE6
Gene ID:6676

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 422-436 amino acids of Human sperm associated antigen 4

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total SPAG4 protein.

Applications:

ELISA WB IHC

Background:

The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.

References:

appl_detail:

Predicted MW: 48kd
ELISA: 1:2000-1:10000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:30-1:150

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