SIRT5 Antibody

Catalog Number:

31267

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NXA8
Gene ID:23408

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 229-242 amino acids of Human sirtuin 5

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total SIRT5 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

References:

appl_detail:

Predicted MW: 22kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF