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P2RY11 Antibody

Catalog Number:

31254
other_names: purinergic receptor P2Y, G-protein coupled, 11, P2Y11

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Genbank No.: NP_002557

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 361-374 amino acids of Human purinergic receptor P2Y, G-protein coupled, 11

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total P2RY11 protein.

Applications:

ELISA WB IHC

Background:

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

References:

appl_detail:

Predicted MW: 40kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

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