MMP19 Antibody

Catalog Number:

31241

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P24844
Gene ID:10398

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide peptide corresponding to a region derived from 404-418 amino acids of human matrix metallopeptidase 19

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total MMP19 protein.

Applications:

ELISA WB

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene.

References:

appl_detail:

Predicted MW: 57kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF