CSF1R Antibody

Catalog Number:

31235

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P22894
Gene ID:4317

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 955-972 amino acids of Human colony stimulating factor 1 receptor

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CSF1R protein.

Applications:

ELISA WB

Background:

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

References:

appl_detail:

Predicted MW: 108kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF