GHSR Antibody

Catalog Number:

31208

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P30968
Gene ID:2798

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 18-32 amino acids of Human growth hormone secretagogue receptor

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total GHSR protein.

Applications:

ELISA WB

Background:

This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

References:

appl_detail:

Predicted MW: 41kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:2000

Datasheet PDF