PTGER2 Antibody

Catalog Number:

31194

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q12952
Gene ID:2300

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 1-13 amino acids of Human prostaglandin E receptor 2 (subtype EP2), 53kDa

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PTGER2 protein.

Applications:

ELISA WB

Background:

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor?(53kDa), also known as?EP2, is a?prostaglandin receptor?for?prostaglandin E2. It is encoded by the human?gene?PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

References:

appl_detail:

Predicted MW: 40kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF