ENPP7 Antibody

Catalog Number:

31192

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P19235
Gene ID:2057

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 290-305 amino acids of Human ectonucleotide pyrophosphatase/phosphodiesterase 7

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ENPP7 protein.

Applications:

ELISA WB IHC

Background:

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7?(E-NPP 7) also known as?alkaline sphingomyelin phosphodiesterase?(Alk-SMase) or?intestinal alkaline sphingomyelinase?is an?enzyme?that in humans is encoded by the?ENPP7?gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.

References:

appl_detail:

Predicted MW: 52kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF