EDNRB Antibody

Catalog Number:

31191

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P43116
Gene ID:5732

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide peptide corresponding to a region derived from 70-84 amino acids of human endothelin receptor type B

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total EDNRB protein.

Applications:

ELISA WB IHC

Background:

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Predicted MW: 50kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF