DEFA1 Antibody

Catalog Number:

31183

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q05193
Gene ID:1759

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 49-63 amino acids of Human Defensin, alpha 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total DEFA1 protein.

Applications:

ELISA WB IHC

Background:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

References:

appl_detail:

Predicted MW: 10kd
ELISA: 1:500-1:5000
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:25-1:50

Datasheet PDF