DRD4 Antibody

Catalog Number:

31181

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P78344
Gene ID:1982

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 2-15 amino acids of Human Dopamine receptor D4

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total DRD4 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

References:

appl_detail:

Predicted MW: 48kd
ELISA: 1:500-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF