RAB6A Antibody

Catalog Number:

31154

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P20340
Gene ID:11096

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 125-139 amino acids of Human Ras-related protein Rab-6A

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total RAB6A protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

References:

appl_detail:

Predicted MW: 24kd
ELISA: 1:2000-1:10000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF