ACE1 Antibody

Catalog Number:

31140

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NP72
Gene ID:22931

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 78-92 amino acids of Human Angiotensin-converting enzyme

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ACE1 protein.

Applications:

ELISA WB

Background:

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

References:

appl_detail:

Predicted MW: 150kd
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:5000

Datasheet PDF