SIRT3 Antibody

Catalog Number:

31123

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P54920
Gene ID:8775

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 126-382 amino acids of human sirtuin 3

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total SIRT3 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

References:

appl_detail:

Predicted MW: 44kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:15-1:50

Datasheet PDF