NPY Antibody

Catalog Number:

31105

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99497
Gene ID:11315

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total NPY protein.

Applications:

ELISA WB

Background:

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

References:

appl_detail:

Predicted MW: 11kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF