MMP15 Antibody

Catalog Number:

31100

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P15531
Gene ID:4830

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 300 amino acids of human matrix metallopeptidase 15 (membrane-inserted)matrix metallopeptidase 15 (membrane-inserted)

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total MMP15 protein.

Applications:

ELISA WB

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

References:

appl_detail:

Predicted MW: 76kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF