MAD2L1 Antibody

Catalog Number:

31095

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P36952
Gene ID:5268

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total MAD2L1 protein.

Applications:

ELISA WB IHC

Background:

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

References:

appl_detail:

Predicted MW: 24kd
ELISA: 1:1000-1:2000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF