GSR Antibody

Catalog Number:

31078

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9Y251
Gene ID:10855

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 274-475 amino acids of human glutathione reductase

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total GSR protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

References:

appl_detail:

Predicted MW: 56kd
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF