CDK9 Antibody

Catalog Number:

31055

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8NC01
Gene ID:51267

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 19-315 amino acids of human cyclin-dependent kinase 9

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CDK9 protein.

Applications:

ELISA WB

Background:

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

References:

appl_detail:

Predicted MW: 53kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF