CBX5 Antibody

Catalog Number:

31049

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P11802
Gene ID:1019

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CBX5 protein.

Applications:

ELISA WB

Background:

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References:

appl_detail:

Predicted MW: 22kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000

Datasheet PDF