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CA3 Antibody

Catalog Number:

31045
other_names: Carbonic anhydrase 3, Car3, CAIII

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9HC52
Gene ID:57332

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to N terminal 260 amino acids of Human Carbonic anhydrase 3

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CA3 protein.

Applications:

ELISA WB IHC

Background:

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.

References:

appl_detail:

Predicted MW: 30kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50

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