ANGPTL3 Antibody

Catalog Number:

31029

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q04695
Gene ID:3872

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ANGPTL3 protein.

Applications:

ELISA WB IHC

Background:

The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.

References:

appl_detail:

Predicted MW: 54kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF