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ACTG1 Antibody

Catalog Number:

31004
other_names: actin, gamma 1, ACT, ACTG, BRWS2, DFNA20, DFNA26

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P15121
Gene ID:231

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 4-379 amino acids of human actin, gamma 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ACTG1 protein.

Applications:

ELISA WB

Background:

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Predicted MW: 42kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

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