1-832-868-1888
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Catalog Number: |
30999 |
| other_names: | ETFA; EMA; GA2; MADD; electron transfer flavoprotein alpha subunit |
Amount: |
100μg |
| calculated_mw: | 35kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P13804 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human ETFA (NP_000117.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF |
Background: |
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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