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PPAN Polyclonal Antibody

Catalog Number:

30908
other_names: PPAN; BXDC3; SSF; SSF-1; SSF1; SSF2; suppressor of SWI4 1 homolog

Amount:

100μg
calculated_mw: 53kDa/55kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9NQ55
NCBI Gene ID:56342

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human PPAN (NP_064615.3).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

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