Acetyl-Histone H4-K8 pAb

Catalog Number:

30871

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P62805
NCBI Gene ID:8370

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human Acetyl-Histone H4-K8

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

References:

appl_detail:

WB 1:1000 - 1:3000
IHC 1:200 - 1:500
IF 1:500 - 1:1000
IP 1:200 - 1:500
ChIP 1:20 - 1:50
ChIPseq 1:20 - 1:50

Datasheet PDF