ORC6 Polyclonal Antibody

Catalog Number:

30651

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9Y5N6
NCBI Gene ID:23594

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human ORC6 (NP_055136.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF