DEFA3 Polyclonal Antibody

Catalog Number:

30649

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P59666
NCBI Gene ID:1668

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human DEFA3 (NP_005208.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF