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RNASEH2B Polyclonal Antibody

Catalog Number:

30626
other_names: RNASEH2B; AGS2; DLEU8; ribonuclease H2 subunit B

Amount:

100μg
calculated_mw: 37kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q5TBB1
NCBI Gene ID:79621

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human RNASEH2B (NP_078846.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

References:

appl_detail:

WB 1:500 - 1:2000

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