FZD7 Polyclonal Antibody

Catalog Number:

30535

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75084
NCBI Gene ID:8324

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human FZD7 (NP_003498.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF